Personalized mRNA Vaccines for Cancer Patients
Vision: To deliver personalized precision (n=1) mRNA cancer vaccine immunotherapies for Cancer Patients in the UK, US, EU in cooperation with leading Cancer Hospitals
Our Mission
To help cancer patients. In the California to consistently beat the “mean survival” for their cancer, with our 2 core products.
To Beat Cancer. Cancer will emerge in 1 of 2 people within their lifetime. Cancer is a tragic disease which causes pain, misery and death. Cancer costs the US Government and Society over $200.7 billion per annum and it’s expected to rise to $245 billion by 2030.
Targeted
Normax California investigational mRNA cancer vaccines will be manufactured for individuals based on the specific molecular features of their tumors which are called neoantigens. Training your immune system to recognize these neoantigen protein targets on the surface of your cancer cells could empower your body to control your cancer.
Personalized
For more than a decade, cancer researchers have been developing a type of treatment known as a personalized cancer vaccine using various technologies, including mRNA and protein fragments, or peptides to target your neoantigens of your cancer. A personalized mRNA vaccine from Normax California could be a safe and effective tool for your doctors to use in the arsenal to fight your cancer.
Rapid Delivery
Normax Calfifornia plans to produce a personalized mRNA cancer vaccine for you, after tissue samples have been collected, within 1 to 2 months. Speed is especially important for individualized cancer vaccination. Ideally, a highly individualized vaccine combination to target your neoantigens should be designed and produced within 10 weeks of taking your tumor biopsy and blood sample.
Partnership with City of Hope
City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the United States, has been recognized as having one of the nation’s Top 5 hospitals for cancer care, according to U.S. News & World Report’s 2024-25 rankings. The recognition marks the latest milestone for City of Hope as it enhances its ability to make a meaningful impact in the lives of patients, families and communities nationwide.
mRNA CANCER VACCINE TECHNOLOGY
Step 1
Identifying the unique mutations of your cancer by comparing the differences of the DNA sequences of your cancer cells and your normal cells.
Step 2
Selecting and testing the patient cancer mutations that could his natural immune system to launch the most effective attack on the cancer cells.
Step 3
Using mRNA vaccine technology to produce the personalized cancer vaccine
mRNA CANCER VACCINE TECHNOLOGY
Clinical Trials
Normax California is initiating clinical trial testing of personalized mRNA vaccines to target individual neoantigens. The goal is a complete and enduring response whereby all signs of the tumor disappear following treatment.
Advanced AI Analytics
The manufacturing process starts with the identification of genetic mutations in a patient’s tumor cells that could give rise to neoantigens. Computer algorithms then predict which neoantigens are most likely to bind to receptors on T cells and stimulate an immune response.
T Cell Education
The vaccine can include genetic sequences for many different neoantigens. The promise of personalized immunotherapy with mRNA vaccines is being able to activate T cells that will specifically recognize individual cancer cells based on their abnormal molecular features.
The Problem: Cancer in the US
Cancer Prevalence in the US
2022
2032
2040
Cancer
Incidence
2022
Cancer
Deaths
YEARLY
Cancer
Oncologists
2023
Cancer Economic Cost in US
YEARLY
